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Ketamine and Post-Herpetic Neuralgia

When the Chicken Pox virus (Herpes Zoster) reactivates, leading to an attack of Shingles, Post-Herpetic Neuralgia (PHN) is the often severe pain that can linger after the blistering rash subsides. This is the experience of millions of Americans every year. PHN is not usually a permanent condition, but it can take months or even years to resolve. The pain can cause stress, and affect the sleep and general well-being of the affected.

Ketamine could help with this persistent burning pain. Besides being shown to have a healing effect on overexcited nerve tissue, Ketamine has been shown to bind to NMDA receptors, preventing the binding of glutamate, and leading to a break in the pain loop and a decrease in the perception of pain.

Even small doses have been shown to be effective. One study of eight patients showed that a single intravenous dose of 0.15 mg/kg of body weight over an infusion time of ten minutes could lead to a “significant” reduction in pain, compared to a placebo with morphine. While Ketamine can be administered in a variety of means, it should be noted that topical administration seems less effective in this case. In one study, one per cent S-Ketamine applied four times per day for 15 days, and one per cent R-Ketamine applied three times daily for three weeks, did not outperform the placebo control group. Intravenous Ketamine infusions have been found to be the fastest acting and most effective means of delivery.

The specialists at Ketamine Infusion for Pain Relief Institute (KIPRI) are here to help. We offer hope to patients suffering from chronic pain by providing a simple and effective therapy. If conventional pain treatments have not worked for you, KIPRI can help you take back control of your life with medically-supervised Ketamine infusion therapy.

 

 

 

 

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